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目的:分析呼吸内科住院患者革兰阴性杆菌感染的临床原因及其耐药性,为临床诊治和合理用药提供参考。方法:选取2015年3月—2016年8月间医院呼吸内科收治的革兰阴性杆菌感染患者52例,从中分离出74株革兰阴性菌,采用药敏试验检测其对抗菌药物的耐药性。结果:从52例呼吸内科住院患者的标本中,分离出革兰阴性杆菌74株(鲍曼不动杆菌14株、阴沟肠杆菌6株、肺炎克雷伯菌20株、大肠埃希杆菌11株、铜绿假单胞菌11株和其他菌株12株);铜绿假单胞菌、鲍曼不动杆菌、肺炎克雷伯菌和阴沟肠杆菌对抗菌药物的耐药率较高。结论:分离出革兰阴性杆菌中,菌株中以肺炎克雷伯菌、鲍曼不动杆菌所占百分率为最高;而铜绿假单胞菌、鲍曼不动杆菌、肺炎克雷伯菌和阴沟肠杆菌对抗菌药物的敏感率为最低。
Objective: To analyze the clinical causes and drug resistance of Gram-negative bacilli inpatients with respiratory medicine and provide reference for clinical diagnosis and rational use of drugs. Methods: From March 2015 to August 2016, 52 patients with Gram-negative bacilli were enrolled in the Department of Respiratory Medicine, 74 strains of Gram-negative bacteria were isolated from them, and their drug resistance to antibiotics was tested by drug sensitivity test . Results: From 52 specimens of inpatients with respiratory medicine, 74 strains of Gram-negative bacilli (14 strains of Acinetobacter baumannii, 6 strains of Enterobacter cloacae, 20 strains of Klebsiella pneumoniae, 11 strains of Escherichia coli, , Pseudomonas aeruginosa 11 and other strains 12); Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae and Enterobacter cloacae antibacterial drug resistance rate is higher. Conclusion: Among the isolates of Gram-negative bacilli, Klebsiella pneumoniae and Acinetobacter baumannii were the highest among the isolates; while Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae and cloacae Enterobacteriae antibacterial drug sensitivity is the lowest.