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自然界的硼除大部分是硼-11外,其中还含有18.84％的同位素硼-10,后者具有強烈的吸收中子而放出α-射线的能力,为此,在1940年Kruger提出在蛋白质中引入一定浓度的硼来作为医学上的治疗。近几年来化学家们合成许多含硼的有机化合物如偶氮染料、二硼酸、带各种取代基(溴、硫、氮等)的芳基硼酸及其酸酐、含硼杂环化合物以及氨基酸类等,企图通过这类化合物能选择地优先引入或集聚在癌细胞中,利用中子
In addition to most of the natural boron boron-11, which also contains 18.84% of the isotope boron-10, which has a strong absorption of neutrons and the release of α-rays, therefore, in 1940 Kruger proposed in the protein The introduction of a certain concentration of boron as a medical treatment. In recent years, chemists have synthesized many boron-containing organic compounds such as azo dyes, diboric acid, aryl boronic acids and anhydrides with various substituents (bromine, sulfur, nitrogen and the like), boron-containing heterocyclic compounds and amino acids , Etc., in an attempt to selectively preferentially introduce or agglutinate cancer cells by such compounds, utilize neutrons