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目的:分析小剂量甲状腺素片在早产儿喂养不耐受治疗中的临床疗效。方法:抽取2014年1月至2015年12月英德市人民医院24例产生喂养不耐受现象的早产儿,依据治疗方式的差异将其分为观察组和对照组,每组12例。对照组予以基础治疗,观察组在基础治疗上予以左旋甲状腺素片,监测所有患儿治疗前和接受治疗1周后血清促甲状腺激素(TSH)、血清游离三碘甲腺原氨酸(FT3)以及血清游离甲状腺素(FT4)水平等生化指标,并且观察两组1周后的临床疗效。结果:观察组患儿FT3水平(1.40±0.39)pmol/L明显大于对照组患儿的(1.09±0.30)pmol/L,同时观察组患儿治疗有效率91.66%,明显高于对照组58.33%,差异具有统计学意义(P<0.05)。结论:对于早产儿产生的喂养不耐受病症,小剂量的相应甲状腺素片能够产生较好的病症改善效果。
Objective: To analyze the clinical efficacy of low-dose thyroxine tablets in the treatment of premature infants intolerant. Methods: Twenty-four preterm infants with feeding intolerance in Yingde People’s Hospital from January 2014 to December 2015 were selected and divided into observation group and control group with 12 cases in each group according to the difference of treatment methods. The control group was given basic treatment. The observation group was treated with levothyroxine for basic treatment. Serum thyrotropin (TSH), serum free triiodothyronine (FT3) And serum free thyroxine (FT4) levels and other biochemical indicators, and observe the clinical efficacy of two groups after 1 week. Results: The level of FT3 in the observation group (1.40 ± 0.39) pmol / L was significantly higher than that in the control group (1.09 ± 0.30) pmol / L, and the effective rate of the observation group was 91.66%, significantly higher than that of the control group (58.33% , The difference was statistically significant (P <0.05). CONCLUSIONS: Small doses of the corresponding thyroxine tablets can produce better disease-modifying outcomes for feeding intolerant conditions in preterm infants.