论文部分内容阅读
目的观察尼莫地平注射液对高血压性脑出血的临床疗效。方法应用前瞻性随机单盲方法,对45例经头颅CT证实的急性脑出血患者,在入院后随机分为治疗组(尼莫地平和甘露醇组)和对照组(单纯甘露醇组)。观察治疗前后神经功能,颅内血肿大小及其周边水肿大小的变化,采用神经功能缺损程度积分及头颅CT上血肿吸收率为指标,并与对照组比较。结果治疗组神经功能恢复,血肿吸收及血肿周边水肿面积等各指标平均减少分数以及CT上血肿吸收率与对照组相比均优于对照组。结论尼莫地平是治疗急性高血压性脑出血的一种疗效肯定的药物,能促进神经功能恢复,促进血肿吸收,抑制脑水肿形成。
Objective To observe the clinical effect of nimodipine injection on hypertensive intracerebral hemorrhage. Methods 45 patients with acute cerebral hemorrhage confirmed by skull CT were randomly divided into treatment group (nimodipine and mannitol group) and control group (mannitol alone group) after the admission. The changes of nerve function, the size of intracranial hematoma and the surrounding edema were observed before and after treatment. The indexes of neurological deficit and cranial hematoma absorption were used as indexes and compared with the control group. Results The neurological function recovery, hematoma absorption and hematoma surrounding edema area and other indicators of the average reduction in scores and on the CT hematoma absorption rate compared with the control group were better than the control group. Conclusion Nimodipine is an effective drug for the treatment of acute hypertensive intracerebral hemorrhage. It can promote the recovery of neurological function, promote the absorption of hematoma, and inhibit the formation of cerebral edema.