论文部分内容阅读
AIM:To determine the prevalence of Helicobacter pylori(H pylori)among dyspeptic patients and to assess therelationship between H pylori infection,blood group,HIVinfection and life style of the patients.METHODS:In a hospital-based cross-sectional study,patients attending Outpatient Department of Universityof Gondar Hospital were enrolled.Socio-demographicinformation was collected using questionnaires.Serumwas analyzed for anti-H pylori IgG antibodies usinga commercial kit.HIV serostatus was determined byenzyme-linked immunosorbent assay(ELISA).Bloodgrouping was performed by slide agglutination tests.RESULTS:A total of 215 dyspeptic patients wereincluded in the study.One hundred and sixteen patients(54%)were females and 99(46%)were males.Anti-Hpylori IgG antibodies were detected in sera of 184(85.6%)patients.The prevalence was significantly higherin patients aged 50 years and above.Twenty point fivepercent of the patients were found to be seropositive forHIV.No significant association was found between sex,ABO blood groups,consumption of spicy diets,socio-economic status and seropositivity for Hpylori.However, alcohol consumption was significantly associated with Hpylori serology.CONCLUSION:The prevalence of H pylori infection isassociated with a history of alcohol intake and older age.The effect of different diet,alcohol and socioeconomicstatus as risk factors for H pylori infection needs furtherstudy.
AIM: To determine the prevalence of Helicobacter pylori (H pylori) among dyspeptic patients and to assess therelationship between H pylori infection, blood group, HIVinfection and life style of the patients. METHHODS: In a hospital-based cross-sectional study, patients attending Outpatient Department of University of Gondar Hospital were enrolled. Socio-demographic information was collected using a questionnaire. Serum was analyzed for anti-H pylori IgG antibodies using a commercial kit. HIV serostatus was determined by enzyme-linked immunosorbent assay (ELISA). Blood grouping was performed by slide agglutination tests .RESULTS: A total of 215 dyspeptic patients wereincluded in the study. One hundred and sixteen patients (54%) were females and 99 (46%) were males. Anti-Hpylori IgG antibodies were detected in sera of 184 The prevalence was significantly higherin patients aged 50 years and above.Twenty points fivepercent of the patients were found to be seropositive forHIV.No significant association wa s found between sex, ABO blood groups, consumption of spicy diets, socio-economic status and seropositivity for Hpylori. However, alcohol consumption was significantly associated with Hpylori serology. CONCLUSION: The prevalence of H pylori infection isassociated with a history of alcohol intake and older age.The effect of different diet, alcohol and socioeconomicstatus as risk factors for H pylori infection needs furtherstudy.