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报道用米索前列醇(前列腺素E_1)引产致子宫破裂2例。1例为22岁(G2P1),血压26.7/13.3kPa(200/100mmHg),宫高约20周孕,子痫发作,颈管可容受一横指,经肼苯哒嗪和硫酸镁稳定病情,并给予米索前列醇200μg,22h20min后宫口开大2cm,再次给予米索前列醇100μg1h30min后自娩1胎儿,胎盘胎膜自娩完整,15min后出现烦燥、子宫松弛,再15min后死亡。尸检见胸腔和心包腔积液,大脑出血,右阔韧带内子宫破裂。另1例为27岁(G4P1),孕35周,血压22.7/16.0kPa(170/120mmHg),重症先兆子痫,持续给予肼苯哒嗪和硫酸镁稳定病情,并
Reported misoprostol (prostaglandin E_1) induced uterine rupture in 2 cases. 1 case was 22 years old (G2P1), blood pressure 26.7 / 13.3kPa (200 / 100mmHg), about 20 weeks pregnant uterus, eclampsia, neck canal can tolerate a horizontal finger, hydralazine and magnesium sulfate stability , And given misoprostol 200μg, 22h20min after the cervix open 2cm, again given misoprostol 100μg1h30min after delivery of a fetus, placental membranes from childbirth complete, 15min after irritability, uterine relaxation, and then died after 15min. Autopsy see thoracic and pericardial effusion, cerebral hemorrhage, the right broad ligament rupture of the uterus. The other 1 case was 27 years old (G4P1), 35 weeks pregnant, blood pressure 22.7 / 16.0kPa (170 / 120mmHg), severe preeclampsia, sustained hydralazine and magnesium sulfate stability and