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药物通过人体皮肤吸收而作用于全身是一种优良的给药途径。透皮给药的优点很多,而主要缺点是药物透皮量较少。使用药物透皮促进剂是增加药物透皮量的一种方法。本研究目的是测定脯氨酸酯的衍生物是否具有促进药物透皮吸收的能力及其对动物中枢神经系统(CNS)的毒性反应。1透?
Drug absorption through the body’s skin and acting on the body is an excellent route of administration. Transdermal administration has many advantages, but the main disadvantage is that the drug transdermal volume is less. Use of drug transdermal enhancers is a way to increase the amount of drug transdermally delivered. The purpose of this study was to determine whether proline ester derivatives have the ability to promote transdermal drug absorption and their toxic effects on the central nervous system (CNS) of animals. 1 through?