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AIM:To evaluate lipid profile in children with coronary artery disease(CAD)in Hyderabad,Sindh,Pakistan.METHODS:The study included 100 children(6-15years),of which 43 were children of young parents(one or both)with recognized CAD,while the other 57 were children with no evidence of CAD(controls).All were evaluated for fasting blood lipid profile.Blood samples were collected from patients with CAD and healthy controls and analysis of the levels of lipid profile were carried out using a kit method on Microlab 300.RESULTS:Children with CAD had significantly higher levels of total serum cholesterol and triglycerides and decreased levels of high density lipoprotein and low density lipoprotein compared to children in the control group.Systolic and diastolic blood pressures were significantly higher,without any significant difference.CONCLUSION:CAD risk factors are significant regarding abnormal lipid levels.Genetic tendency seems to be important in the development of CAD in children.
AIM: To evaluate lipid profile in children with coronary artery disease (CAD) in Hyderabad, Sindh, Pakistan. METHHODS: The study included 100 children (6-15years), of which 43 were children of young parents (one or both) with recognized CAD, while the other 57 were children with no evidence of CAD (controls). All were evaluated as fasting blood lipid profile. Blood samples were collected from patients with CAD and healthy controls and analysis of the levels of lipid profile were carried out using using a kit method on Microlab 300.RESULTS: Children with CAD had significantly higher levels of total serum cholesterol and triglycerides and decreased levels of high density lipoprotein and low density lipoprotein compared to children in the control group. Systolic and diastolic blood pressures were significantly higher, without any significant difference. CONCLUSION: CAD risk factors are significant for abnormal lipid levels. Genetic trends seems to be important in the development of CAD in children.