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〔目的〕探讨肿瘤患者血清总唾液酸的临床检测意义。〔方法〕采用化学比色法对多种肿瘤患者进行血清总唾液酸(TSA)分析。〔结果〕肿瘤病人血清TSA含量比正常人明显增高,分析显示,食管癌(661%,0191)、肺癌(714%,0228)、卵巢癌(696%,0216)、宫颈癌(716%,0196)的TSA阳性检出率及均值与正常人血清(33%,0154)有显著性差异(P<0.05)。〔结论〕提示血清TSA含量检测可作为一种肿瘤早期诊断指标。
[Objective] To explore the clinical significance of serum total sialic acid in patients with cancer. [Methods] Serum total sialic acid (TSA) analysis was performed on a variety of cancer patients by chemical colorimetry. 〔Results〕 Serum TSA levels in tumor patients were significantly higher than those in normal subjects. Analysis showed that esophageal cancer (661%, 0191), lung cancer (714%, 0228), ovarian cancer (696%, 0216), cervical cancer (716%, 0196). The positive rate and mean value of TSA were significantly different from normal human serum (33%, 0154) (P<0.05). [Conclusion] The serum TSA level can be used as an indicator for early diagnosis of tumors.