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自１９８３年ＭｃＬａｆｆｅｒｔｙ等［１］开发串联质谱技术（ＭＳ／ＭＳ）以来，经过短短十几年的发展，串联质谱已成为一种成熟的技术，在许多领域特别是在药学领域发挥了巨大作用。串联质谱法是指质量分离的质谱检测技术，有分离、结构解析同步完成的特点，能直接分析混合
Since the development of tandem mass spectrometry (MS / MS) by McLafferty et al. [1] in 1983, tandem mass spectrometry has become a mature technology after more than a decade of development and has played a great role in many fields, especially in the field of pharmacy . Tandem mass spectrometry refers to the mass separation of mass spectrometry detection technology, with separation, structural analysis of the characteristics of simultaneous completion of direct analysis of mixed