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目的通过对儿童过敏性紫癜(HSP)的临床表现和实验室检查进行分析,探讨其出现紫癜性肾炎的相关临床因素。方法回顾性分析114例儿童过敏性紫癜的临床资料,分为尿检异常组(n=65例)和正常组(n=49例),对其性别、年龄、临床表现及实验室检查等进行统计分析。结果异常组的>7岁比例、男患儿比例、皮疹持续时间、皮疹反复、心脏受累、3个系统以上受累高于正常组。平均发病年龄、脑电图异常、关节、消化道症状方面,两组类似。结论男性儿童出现紫癜性肾炎者较多,且临床表现为多发症状者易出现肾损害。
Objective To analyze the clinical manifestations and laboratory tests of Henoch-Schonlein purpura (HSP) in children and discuss the clinical factors related to purpuric nephritis. Methods The clinical data of 114 cases of Henoch-Schonlein purpura in children were retrospectively analyzed. The data were divided into three groups (n = 65) and normal group (n = 49), and their gender, age, clinical manifestations and laboratory tests were statistically analyzed analysis. Results In the abnormal group, the proportion of> 7 years old, the proportion of male children, the duration of rash, repeated rashes and heart involvement were higher in the three systems than in the normal group. Mean age at onset, EEG abnormalities, joint, gastrointestinal symptoms, two groups similar. Conclusion There are more children with purpuric nephritis, and the clinical manifestations of multiple symptoms are prone to kidney damage.