【摘 要】
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Since the publication of the DRiP (defective ribosomal product) hypothesis in 1996,numerous studies have addressed the contribution of DRiPs to generating viral antigenic peptides for CD8+ T cell immunosurveillance.Here,we review studies characterizing th
【机 构】
：
Cellular Biology Section, Laboratory of Viral Diseases,National Institute of Allergy and Infectious
论文部分内容阅读
Since the publication of the DRiP (defective ribosomal product) hypothesis in 1996,numerous studies have addressed the contribution of DRiPs to generating viral antigenic peptides for CD8+ T cell immunosurveillance.Here,we review studies characterizing the generation of antigenic peptides from influenza A virus encoded DRiPs,discuss the many remaining mysteries regarding the nature of their co-translational generation,and speculate on where the future might lead.
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