论文部分内容阅读
目的探讨近20年来感染性心内膜炎(IE)的皮肤粘膜损害的临床变迁。方法将118例IE分为1988～1997年53例(A组)和1998～2007年65例(B组),对其基础心脏病因、致病菌、皮肤粘膜损害表现进行对比分析。结果①基础病因中,风湿性心脏瓣膜病下降,先天性心脏病、无基础心脏病因上升;②致病菌中,草绿色链球菌下降,金黄色葡萄球菌上升;③所有皮肤粘膜损害减少,溃疡增多(上述改变均P<0.05)。结论近20年来IE基础心脏病、致病菌、皮肤粘膜损害表现均发生了改变,皮肤粘膜损害表现对IE的诊断、治疗具有一定的参考意义。
Objective To investigate the clinical changes of skin and mucosal lesions in infective endocarditis (IE) in recent 20 years. Methods A total of 118 cases of IE were divided into three groups (group A) from 1988 to 1997 (group A) and 65 cases from 1998 to 2007 (group B). Their basic causes of heart disease, pathogenic bacteria and mucocutaneous lesions were compared. Results ① The underlying causes were rheumatic valvular disease, congenital heart disease and no underlying heart disease; ② pathogenic bacteria, Streptococcus viridans decreased and Staphylococcus aureus increased; ③ all skin and mucous membrane lesions were reduced and ulcers Increased (P <0.05 for all above changes). Conclusion In the past 20 years, the manifestations of heart diseases, pathogenic bacteria and mucocutaneous lesions in IE have changed. The performance of cutaneous mucosa lesions has certain reference value for the diagnosis and treatment of IE.