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作者对肝疾病婴儿的血清天冬氨酸转氨酶与丙氨酸转氨酶之比(AST/ALT)作了评价,认为用在早期做为婴儿肝疾病预后指标的简单、方便和可靠的有用方法。病例与方法依据临床、微生物学、放射学、生物化学及组织学检查确诊,分析了1976年10月到1988年9月间慢性肝疾病婴儿73例(男39,女34),其中肝外胆道闭锁42例、巨细胞包涵体病毒性肝炎12例、特发性新生儿肝炎11例、α—1抗胰蛋白酶缺乏性肝病6例、肝动脉发育不良2例,有肝硬化、门脉高压、食道静脉曲张、腹水、肝移植或死亡者为恶性转归组
The authors evaluated the serum AST / ALT ratio in infants with liver disease as a simple, convenient and reliable method of early use as a prognostic indicator of infant liver disease. The cases and methods were confirmed by clinical, microbiological, radiological, biochemical and histological examination. Totally 73 infants (39 males and 34 females) with chronic liver disease were analyzed from October 1976 to September 1988, of which extrahepatic biliary tract 42 cases of atresia, cytomegalovirus inclusion body viral hepatitis in 12 cases, idiopathic neonatal hepatitis in 11 cases, α-1 antitrypsin-deficient liver disease in 6 cases, hepatic artery dysplasia in 2 cases, cirrhosis, portal hypertension, Esophageal varices, ascites, liver transplantation or death were malignant outcome group