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Background: The foreign bone material of the same species was widely applied, while for the multiple manipulating processes, it got lots of chances to be infected, especially for the bone manufacturing, the pollution odds increased greatly, so the sterilizing process was most important. Objective: To observe the sterilizing effects of ZMW anprolene case on foreign bone materials to find a safe and economic disinfecting way. Unit:First attached hospital of the Shihezi medical university. Subject:The manipulating method of the foreign bone material of the same species: In clean environment., bone was got in 2 hours after death of the donor, soft tissue was removed and it was made to foreign bone material of 0.5 cm× 0.5 cm× 2 cm, it was washed with water and marinated till the water got clear, then washed with distilled water repeatedly, lipid was removed with 1:1 chloroform and methanol for 4 hours at room temperature, calcium was removed with 0.6 mol/L HCL for 4 hours at 4 ℃ , it was washed with distilled water till the pH was 6.5. The bone material after treating were divided into two groups, one was dried in common air dried to make wet one plantation material and the other one was dried in 37℃ roasting case to make dry bone plantation material. They were both put in double polyethylene bags and sealed with standard sealing machine, the weight was 5 g, rn