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目的:比较乳酸左氧氟沙星与头孢唑肟对急性水肿型胆源性胰腺炎患者抗感染的疗效。方法:选取医院2014年12月—2016年12月期间收治的急性水肿型胆源性胰腺炎患者92例资料,采用随机分组法将其分为对照组和治疗组(每组46例);对照组患者给予头孢唑肟治疗,治疗组患者给予乳酸左氧氟沙星治疗,比较两组患者治疗后的总有效率和用药期间不良反应的发生率,以及治疗后症状消失时间和治疗的总时间。结果:治疗组患者用药后的总有效率为91.30%高于对照组为71.74%(P<0.05),胰腺炎症状消失时间和用药总时间均优于对照组(P<0.05),用药期间不良反应的发生率为4.35%低于对照组为17.39%(P<0.05)。结论:乳酸左氧氟沙星对急性水肿型胆源性胰腺炎患者抗感染的疗效优于头孢唑肟,且不良反应的发生率较低。
Objective: To compare the efficacy of levofloxacin lactate and ceftizoxime against infection in patients with acute edematous biliary pancreatitis. Methods: A total of 92 patients with acute edematous biliary pancreatitis admitted from December 2014 to December 2016 in our hospital were selected and randomly divided into control group and treatment group (46 cases in each group). The control group Patients in the treatment group were treated with ceftizoxime. Patients in the treatment group were treated with levofloxacin lactate. The total effective rate and the incidence of adverse reactions during the treatment were compared between the two groups. The duration of symptom disappearance and total treatment time were compared between the two groups. Results: The total effective rate of the treatment group was 91.30% higher than that of the control group (71.74%, P <0.05), the disappearance time of the pancreatitis and the total time of treatment were better than the control group (P <0.05) The incidence of the reaction was 4.35% lower than the control group was 17.39% (P <0.05). Conclusion: Levofloxacin lactate is more effective than ceftizoxime in the treatment of patients with acute edematous biliary pancreatitis and the incidence of adverse reactions is lower.