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作者对５７例年龄在３个月内息巨细胞病毒（ＣＭＶ）肝炎的婴儿，分组进行干扰素（ＩＦＮ）治疗观察。治疗组（ｎ＝３０）在用静脉ＶｉｔＣ加肌苷的基础上加用γ－ＩＦＮ１０￣６ｕ／ｄ肌注，连续１０天。对照组（ｎ＝２７），单用静脉ＶｉｔＣ加肌苷，连续１０天。其后两组病人均口服ＶｉｔＣ、肌苷至一个月。结果显示，γ－ＩＦＮ治疗组与对照组比疗效有显著性差异。黄疽消退平均提前１５．２６天（Ｐ＜０．００５）；肝脏肿大恢复正常提前２９；８９天（Ｐ＜０．００１），ＳＧＰＴ恢复正常，平均提前１４．２６天（Ｐ＜０．０１）。两组在１个月及２个月的痊愈率分别为４３．０％、１８．５％及９０．Ｏ％、４８．Ｏ％（Ｐ＜０．０５）。
The authors performed an IFN treatment in 57 infants with CMV hepatitis within 3 months. Treatment group (n = 30) with intravenous vitamin C plus inosine plus γ-IFN10 ~ 6u / d intramuscular injection for 10 days. The control group (n = 27) received intravenous VitC plus inosine alone for 10 consecutive days. The two groups of patients after oral administration of VitC, inosine to a month. The results showed that, γ-IFN treatment group and the control group, the effect was significantly different. The regression of jaundice averaged 15.26 days earlier (P <0.005); liver enlargement returned to normal 29 and 89 days earlier (P <0.001) and SGPT returned to normal with an average of 14.26 days (P <0. 01). The cure rates at 1 month and 2 months in both groups were 43.0%, 18.5% and 90% respectively. O%, 48. O% (P <0.05).