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本文分析我科1957—1972年底收治的女性原发乳腺癌331例的远期疗效。中间年龄47.3岁。乳腺侧别发病率相似,外上象限为好发部位。根治术组5年生存率Ⅰ期为87.5%,Ⅱ期为66%,Ⅲ期为38.2%,优于单纯全乳切除术组。Ⅲ期乳癌根治术组手术加放疗的疗效较单纯手术组为优(5年生存率分别为54.2%和38.1%),说明手术加放疗可以提高晚期乳腺癌的远期疗效。分析影响预后的因素示原发灶越大、腋窝淋巴结转移越严重而预后越差。按乳腺癌国际组织学分型、分级,对249例浸润性癌进行比较,结果病理分级越高,预后越差。最后讨论了乳腺癌的治疗问题。
This article analyzes the long-term efficacy of 331 women with primary breast cancer admitted to our hospital from the end of 1957-1972. The middle age is 47.3 years old. The incidence of breast side similar to the outer quadrant as a good site. The 5-year survival rate in the radical surgery group was 87.5%, 66% in phase II, and 38.2% in phase III, which was superior to that of simple mastectomy alone. The curative effect of surgery plus radiotherapy in the stage III radical mastectomy group was better than that in the simple surgery group (5-year survival rate was 54.2% and 38.1%, respectively), indicating that surgery plus radiotherapy can improve the long-term efficacy of advanced breast cancer. Analyzing the factors that influence the prognosis shows that the larger the primary lesion, the more severe the axillary lymph node metastasis and the worse the prognosis. According to the classification and classification of breast cancer international tissue, 249 cases of invasive cancer were compared. As a result, the higher the pathological grade, the worse the prognosis. Finally discussed the treatment of breast cancer.