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目的研究成人非酒精性脂肪性肝病(NAFLD)与代谢综合征(MS)的关系。方法以175例NAFLD患者为病例组,54名非脂肪性肝病体检者为对照组,检测2组的收缩压(SBP)、舒张压(DBP)、腰围(WI)、甘油三酯(TG)、空腹血糖(FBG)、高密度脂蛋白胆固醇(HDL-C)。结果病例组WI、SBP、TG、FBG等指标均高于对照组(分别t=3.790,3.688,2.825,3.251,3.429,2.635,均P<0.01);HDL-C低于对照组(t=2.849,P<0.01);中心性肥胖、高血压、高TG血症、低HDL-C血症、高血糖及MS的患病率高于对照组(分别χ2=29.02,8.64,11.37,6.51,11.72,9.65,均P<0.01),合并MS组分≥3项者的比例高于对照组(χ2=6.15,P<0.05),合并MS组分≤1项者的比例低于对照组(χ2=26.29,P<0.01)。结论NAFLD是MS的组成成分之一,NAFLD可用于预测代谢紊乱危险因素的聚集。
Objective To study the relationship between adult non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS). Methods 175 cases of NAFLD patients as the case group and 54 non-fatty liver disease as the control group, the systolic blood pressure (SBP), diastolic blood pressure (DBP), waist circumference (WI), triglyceride (TG) Fasting blood glucose (FBG), high-density lipoprotein cholesterol (HDL-C). Results The indexes of WI, SBP, TG and FBG in case group were higher than those in control group (t = 3.790,3.688,2.825,3.251,3.429,2.635, all P <0.01); HDL-C was lower than that in control group , P <0.01). The prevalence of central obesity, hypertension, hypercholesteremia, hypo HDL-C, hyperglycemia and MS was higher than that of the control group (χ2 = 29.02,8.64,11.37,6.51,11.72 , 9.65, all P <0.01). The proportion of those with MS ≥ 3 was higher than that of the control group (χ2 = 6.15, P <0.05) 26.29, P <0.01). Conclusion NAFLD is one of the components of MS. NAFLD can be used to predict the aggregation of risk factors for metabolic disorders.