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目的:观察乌灵胶囊联合尼莫地平片治疗紧张型头痛的临床疗效。方法:将2011年2月至2013年8月收治的紧张型头痛患者68例随机分为治疗组和对照组各34例,对照组仅应用尼莫地平片治疗,治疗组在对照组治疗的基础上加用乌灵胶囊3粒/次,3次/d,疗程4周。两组根据临床相关症状(头痛程度、发作频率、持续时间)改善情况进行疗效评价,并于治疗前后行汉密尔顿焦虑量表(HAMA)和抑郁量表(HAMD)评分。结果:治疗组治愈11例,显效14例,好转6例,无效3例,总有效率91.17%;对照组治愈6例,显效11例,好转9例,无效8例。总有效率76.4%,治疗后治疗组的总有效率明显高于对照组(P<0.01)。两组治疗后的焦虑和抑郁评分均优于治疗前,但治疗组明显优于对照组(P<0.01)。结论:在尼莫地平治疗紧张型头痛的基础上,联合乌灵胶囊可提高疗效。建议临床推广应用。
Objective: To observe the clinical effect of Wuling capsule combined with Nimodipine in the treatment of tension-type headache. Methods: Sixty-eight patients with tension-type headache who were admitted from February 2011 to August 2013 were randomly divided into treatment group and control group, 34 cases each. The control group was treated with nimodipine alone. The treatment group was treated with the control group Wuling capsule plus 3 capsules / time, 3 times / d, treatment for 4 weeks. The two groups were evaluated according to the clinical symptoms (headache degree, frequency and duration of headache), and the HAMA and HAMD scores before and after treatment. Results: In the treatment group, 11 cases were cured, 14 cases markedly improved, 6 cases improved, 3 cases ineffective, and the total effective rate was 91.17%. In the control group, 6 cases were cured, 11 cases markedly improved, 9 cases improved, and 8 cases ineffective. The total effective rate was 76.4%. After treatment, the total effective rate of the treatment group was significantly higher than that of the control group (P <0.01). The scores of anxiety and depression after treatment in both groups were better than those before treatment, but the treatment group was significantly better than the control group (P <0.01). Conclusion: Nimodipine in the treatment of tension-based headache, combined with Wuling capsule can improve the curative effect. Recommended clinical application.