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目的探讨经颈静脉下腔静脉滤器植入联合逆行插管小剂量尿激酶溶栓治疗下肢深静脉血栓(DVT)的方法和疗效。方法2003年8月-2007年9月,对45例下肢DVT患者宴施下腔静脉滤器植入联合逆行插管小剂量尿激酶接触性溶栓术。其中10侧患肢溶栓后残存狭窄的病例行球囊扩张,对6例扩张不满意者行支架置入。结果昕有病例均成功植入腔静脉滤器,45例患者共49侧患肢插管成功率为100%。屎激酶总剂量平均360万U,留管时间平均7天(3-13天)。血栓完全溶解32肢,部分溶解17肢。结论经颈静脉置入下腔静脉滤器并逆行插管小剂量尿激酶溶栓治疗下肢DVT操作简便,安全有效。
Objective To investigate the method and efficacy of intravenous low-dose urokinase thrombolysis in the treatment of deep venous thrombosis of the lower extremities through transjugular inferior vena cava filter implantation. Methods From August 2003 to September 2007, 45 cases of lower extremity DVT were treated with inferior vena cava filter implantation and retrograde intubation with low-dose urokinase-contact thrombolysis. One of the 10 patients with thrombolytic residual stenosis cases after balloon dilatation, 6 patients were not satisfied with stent placement. Results Xin cases were successfully implanted in the vena cava filter, a total of 45 patients with a total of 49 side limb intubation success rate was 100%. Total feces kinase total average 3.6 million U, leaving an average of 7 days (3-13 days). Thrombus completely dissolves 32 limbs, partially dissolves 17 limbs. Conclusions It is safe and effective to treat lower extremity DVT through the jugular vein inserted into the inferior vena cava filter and retrograde intubation of low-dose urokinase thrombolysis.