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目的通过不同口腔护理预防重型再生障碍性贫血患者溃疡的发生,提高患者生存质量。方法比较生理盐水加碳酸氢钠、碳酸氢钠加呋喃西林和庆大霉素加维生素B123组漱口液应用于口腔护理,观察患者溃疡发生率。结果生理盐水加碳酸氢钠组和碳酸氢钠加呋喃西林组溃疡发生率分别为50%、45%,明显高于庆大霉素加维生素B12组的9%。结论庆大霉素加维生素B12漱口液可以有效预防再生障碍性贫血患者溃疡的发生,加强口腔护理,明显提高患者的生命质量,改善患者负面情绪,增强患者信心,提高治疗效果,值得推广。
Objective To prevent the occurrence of ulcer in patients with severe aplastic anemia by different oral care to improve the quality of life of patients. Methods Compared with saline plus sodium bicarbonate, sodium bicarbonate and nitrofurazone and gentamicin plus vitamin B123 group mouthwash applied to oral care, observed the incidence of ulcer patients. Results The incidence of ulcer in saline plus sodium bicarbonate group and sodium bicarbonate plus nitrofin group was 50% and 45%, respectively, which was significantly higher than that of gentamicin plus vitamin B12 group (9%). Conclusions Gentamicin plus vitamin B12 gargle can effectively prevent the occurrence of ulcer in patients with aplastic anemia, enhance oral care, improve the quality of life of patients, improve the negative emotions of patients, enhance the confidence of patients and improve the therapeutic effect. It is worth promoting.