论文部分内容阅读
目的对小儿EB病毒感染的临床症状、体征,实验室检查及误诊情况进行综合分析,以提高EB病毒感染的早期诊断水平。方法采用回顾性研究方法,对我院2013年1月~2014年12月用酶联免疫吸附法(ELISA)检测EB病毒VCAIg M抗体诊断EB病毒感染56例的临床资料进行分析。结果 EB病毒感染多表现为发热、咽痛、淋巴结肿大、肝脾肿大,亦可出现皮疹、眼睑水肿、咳嗽、黄疸、乏力、面色苍白、腹痛、抽搐等症状。实验室检查外周血象白细胞增高,单核细胞增高,部分患儿异型淋巴细胞增高,早期EB病毒VCA-Ig M抗体阳性。本组误诊17例,误诊原因主要为早期症状隐匿,体征少,以其他系统感染为主要表现。结论小儿EB病毒感染症状和体征多种多样,并且容易累及全身多个脏器,容易误诊,EB病毒VCA-Ig M抗体检测有利于早期诊断,避免误诊。
Objective To analyze the clinical symptoms, signs, laboratory tests and misdiagnosis of EB virus infection in children so as to improve the early diagnosis of EBV infection. Methods A retrospective study was conducted to analyze the clinical data of 56 patients with Epstein-Barr virus (EBV) infection detected by enzyme-linked immunosorbent assay (ELISA) of Epstein-Barr virus VCAIg M antibody in our hospital from January 2013 to December 2014. Results EB virus infection manifested as fever, sore throat, swollen lymph nodes, hepatosplenomegaly, rashes, eyelid edema, cough, jaundice, fatigue, pale, abdominal pain, convulsions and other symptoms. Laboratory tests of peripheral blood leukocytes, monocytes increased, some children with atypical lymphocytes increased early EBV VCA-Ig M antibody positive. The group of misdiagnosis in 17 cases, the main cause of misdiagnosis of the early symptoms of occult, less signs, with other systemic infections as the main performance. Conclusions There are many symptoms and signs of EB virus infection in children and it is easy to be involved in multiple organs of the body and is easily misdiagnosed. The detection of Epstein-Barr virus VCA-Ig M antibody is helpful for early diagnosis and avoids misdiagnosis.