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目的：为进一步了解巩膜加固术后的组织学改变。方法：选用白色家兔为实验对象，采用人体巩膜施行巩膜加固术，于术后不同时期分批处死动物，并对手术区巩膜进行组织学检查结果：术后1－2周，为炎症浸润期：术后1－2个月为肉芽肿及新生血管增殖期，植片与巩膜粘连；术后3－6月，纤维母细胞形成，植片与巩膜完全愈合，形成“新巩膜”。实验结果为后巩膜加固术提供了理论根据。
Objective: To further understand the histological changes after sclerectomy. Methods: The white rabbits were selected as the experimental subjects. Scleral reinforcement was performed on the human sclera. Animals were sacrificed in batches at different stages after operation. The histological examination of the sclera in the surgical field was performed. Results: 1-2 weeks postoperatively, : 1-2 months after the granuloma and neovascularization, graft and scleral adhesions; 3-6 months after the formation of fibroblasts, the plantar and sclera completely healed, forming a “new sclera.” The experimental results provide a theoretical basis for posterior scleral reinforcement.