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肝素是临床上常用的抗凝药物。近年来国外作者发现其对间质源性细胞，如血管平滑肌细胞、3T3成纤维细胞、肝储脂细胞等具有明显的抗增生作用[1]。肾小球系膜细胞是一种在结构和功能上十分相似于血管平滑肌细胞的血管周细胞。本实验通过建立人肾小球系膜细胞株，观察肝素对该细
Heparin is commonly used in clinical anticoagulant drugs. In recent years, foreign authors found that they have obvious anti-proliferative effects on interstitial-derived cells such as vascular smooth muscle cells, 3T3 fibroblasts, hepatic lipid storage cells, etc. [1]. Glomerular mesangial cells are perivascular cells that are structurally and functionally similar to vascular smooth muscle cells. In this experiment, we established a human glomerular mesangial cell line to observe the fineness of heparin