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作者遇有1例因服用常规剂量异烟肼而引起惊厥反应的患者,现报道如下。患者男,21岁,住院号104019。因左侧胸痛、干咳伴午后低热1个月而于1991年12月12日入院。既往身体健康,无惊厥史及神经系统疾病史。查体:神志清楚,颈软,左下肺呼吸音减弱,心脏(-),肝脾(-),神经系统(-)。血常规、血清电解质、血糖、肝肾功能及心电图检查均正常;血沉40 mm/h,OT 1:10000(+)。胸片及B超均显示左下胸腔少量积液,胸液检验为草黄色渗出液、未检出细菌及抗酸杆菌。诊断为结核性胸膜炎。故服用异烟肼300mg/
The authors encountered in 1 case because of taking conventional doses of isoniazid caused convulsions in patients are reported below. Patient male, 21 years old, hospital number 104019. On the left side of the chest pain, dry cough with fever in the afternoon 1 month and was admitted on December 12, 1991. Past physical health, no history of convulsions and nervous system diseases. Physical examination: conscious, neck soft, lower left lung breath sounds weakened, heart (-), liver and spleen (-), nervous system (-). Blood routine, serum electrolytes, blood glucose, liver and kidney function and ECG were normal; ESR 40 mm / h, OT 1: 10000 (+). Chest radiographs and B-ultrasound showed a small amount of effusion in the left lower thorax. The pleural fluid was yellowish exudate and no bacteria or acid-fast bacilli were detected. Diagnosis of tuberculous pleurisy. So taking isoniazid 300mg /