The clinical efficiency and safety of bisorpolol hydrochlorothiazide in patients with mild to modera

• 作 者: 姜红
• 机 构: Dept Cardiol Sino-Japan Friendship Hosp Beijing 100029,
• 出 处: China Medical Abstracts(Internal Medicine)
• 发表日期: 2006年04期
• 关键词: moderate hypertensive placebo systolic diastolic smoothness trough ABPM

Objective To investigate the efficacy and safety of bisorpolol/hydroehlorothiazide (Lodoz) in patients with mild and moderate essential hypertension. Methods After 2 weeks of placebo run-in period, 90 hypertensive patients with sitting diastolic blood pressure (DBP) between 95 and 109 mm Hg(1 mm Hg =0. 133 kPa) and systolic blood pressure (SBP) below 180 mm Hg were treated by Lodoz(2. 5 mg/6. 25 mg/day) for 4 weeks.

Objective To investigate the efficacy and safety of bisorpolol / hydroehlorothiazide (Lodoz) in patients with mild and moderate essential hypertension. Methods After 2 weeks of placebo run-in period, 90 hypertensive patients with sitting diastolic blood pressure (DBP) between 95 and 109 mm Hg (1 mm Hg = 0.133 kPa) and systolic blood pressure (SBP) below 180 mm Hg were treated by Lodoz (2.5 mg / 6. 25 mg / day) for 4 weeks.