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目的探讨早产新生儿缺氧缺血性脑病(HIE)的CT表现及其临床意义。方法回顾分析61例早产儿HIE临床与CT表现。结果轻度HIE12例,中度36例,重度13例,均合并不同程度颅内出血。治疗后CT复查23例,其中治疗3个月后CT复查显示10例轻度,4例中度和3例重度HIE吸收好转;2例中度和4例重度HIE,CT表现为蛛网膜下腔增宽,其中2例重度仍见弥漫性的密度灶;半年后2例中度和2例重度HIE蛛网膜下腔增宽消失,2例重度HIE遗留脑萎缩及脑软化灶,临床表现为脑瘫、智力低下。结论 CT扫描对早产儿HIE可作出准确的诊断和分度,能为临床治疗、观察疗效及评价癒后提供重要的信息。
Objective To investigate the CT findings and its clinical significance of premature neonates with hypoxic-ischemic encephalopathy (HIE). Methods The clinical and CT findings of 61 preterm infants with HIE were retrospectively analyzed. Results mild HIE in 12 cases, moderate in 36 cases, severe in 13 cases, all with varying degrees of intracranial hemorrhage. After treatment, 23 cases were examined by CT, of which 10 cases were mild, 4 cases were moderate and 3 cases were severe HIE absorption after 3 months of treatment; 2 cases of moderate and 4 cases of severe HIE, CT showed subarachnoid Widened, of which 2 cases still showed diffuse dense density; 2 cases of moderate and 2 cases of severe HIE subarachnoid widened disappear in 2 cases, severe HIE left brain atrophy and cerebral softening lesions, the clinical manifestations of cerebral palsy ,low IQ. Conclusion CT scan can accurately diagnose and classify HIE in preterm infants, which can provide important information for clinical treatment, observation of curative effect and evaluation of prognosis.