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镉对人体健康的意义镉是关系到整个人群健康的有毒微量元素,在人体肾脏中的生物半减期长达10～30年。当肾皮质镉浓度达200mg/kg左右时,肾小管受损并出现尿镉显著升高,这一损害也使尿中钙、葡萄糖、氨基酸和低分子量蛋白排出增加。镉在组织中大部分以金属硫蛋白的结合形式存在,它是亚细胞结构中的一种低分子量蛋白,其合成可能由镉诱导并被认为具有保护性的“贮藏”功能。估计长期食物摄入平均0.200 mg/日镉的人群将有10%的人肾皮质镉超过临界浓度,并
The significance of cadmium on human health Cadmium is a toxic microelement that is related to the health of the entire population. The biological half-life reduction in human kidneys lasts for 10 to 30 years. When renal cortical cadmium concentration of about 200mg / kg, tubular damage and urinary cadmium was significantly increased, this damage also makes the urinary calcium, glucose, amino acids and low molecular weight protein excretion increased. Cadmium is present mostly in the form of metallothionein, a low-molecular-weight protein found in subcellular structures whose synthesis may be induced by cadmium and considered to be protective “storage”. It is estimated that 10% of human renal cortical cadmium estimated to have a long-term food intake of 0.200 mg / day of cadmium will exceed the critical concentration and