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氯乙烯是日益重要的化工原料,除用作制造聚氯乙烯塑料之外,还可制其他树脂,也可用作溶剂、喷雾剂等,全世界年产量约1,200万吨。接触人群不少。1970年Viola报告了氯乙烯使大鼠致癌的实验,大鼠吸入30,000 ppm氯乙烯,每天4小时,每周5次,共10个月,结果皮肤、肺和骨产生肿瘤。作者认为Viola等所用浓度太高,于是又设计了一系列实验,作进一步的研究,并对动物种属、给予剂量和时限等因
Vinyl chloride is an increasingly important chemical raw material. Apart from being used in the manufacture of polyvinyl chloride (PVC) plastic, it can be made into other resins as well as solvents, sprays and the like. The annual output in the world is about 12 million tons. A lot of contact with the crowd. In 1970, Viola reported the carcinogenicity of vinyl chloride to rats. Rats inhaled 30,000 ppm of vinyl chloride for 4 hours a day for 5 months, for a total of 10 months, resulting in tumors of the skin, lungs and bone. The authors consider Viola and other concentrations used too high, so they designed a series of experiments for further study and animal species, giving dose and time limit and other factors