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目的结合文献复习,提高膀胱癌肉瘤的诊治水平。方法回顾分析2例膀胱癌肉瘤患者的临床和病理资料。男女各1例,均以无痛性肉眼血尿为主要症状,B超或CT提示膀胱占位,膀胱镜下见膀胱内肿物,活检病理2例均提示移行细胞癌。结果2例均行膀胱部分切除,术后病理均为膀胱癌肉瘤,显微镜下主要由高分化移行细胞癌和肉瘤成分组成。免疫组化显示:CK及Vimen-tin反应均为阳性。结论诊断依赖病理及免疫组化检查,治疗以根治性手术为主,预后不良。
Objective To review the literature to improve the diagnosis and treatment of bladder cancer. Methods Retrospective analysis of 2 cases of bladder cancer sarcoma clinical and pathological data. Men and women in 1 case, all with painless gross hematuria as the main symptom, B-ultrasound or CT prompted bladder space, cystoscopy see intra-bladder tumor biopsy pathology in 2 cases were prompted transitional cell carcinoma. Results All the 2 cases underwent partial resection of the bladder. The postoperative pathology was all bladder cancer sarcoma. Microscopically, it was mainly composed of highly differentiated transitional cell carcinoma and sarcoma. Immunohistochemistry showed: CK and Vimen-tin reaction were positive. Conclusion The diagnosis depends on the pathological and immunohistochemical examination. The treatment is mainly based on radical surgery and the prognosis is poor.