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目的分析缺血性脑卒中患者血清超敏C反应蛋白(hs-CRP)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)水平的相关性。方法选取缺血性脑卒中患者107例作为试验组,另选取同时期进入该院体检的健康体检者107例作为对照组,分别检测2组血清hs-CRP、FT3、FT4水平。结果试验组血清hs-CRP水平高于对照组,而血清FT3、FT4水平均显著低于对照组,差异均有统计学意义(P<0.05)。血清hs-CRP水平与FT3水平呈明显负相关(r=-0.643,P<0.05),hs-CRP水平和FT4水平呈明显负相关(r=-0.812,P<0.05),FT3水平与FT4水平亦呈明显正相关(r=0.811,P<0.05)。结论血清中hs-CRP与FT3、FT4水平呈负相关,而FT3与FT4水平呈正相关,在临床上可以联合三者进行缺血性脑卒中的辅助诊断,可以作为常规的实验室检查指标。
Objective To analyze the correlation between serum hs-CRP, FT3 and FT4 in patients with ischemic stroke. Methods A total of 107 patients with ischemic stroke were selected as the experimental group. 107 healthy subjects were enrolled in this study. Serum levels of hs-CRP, FT3 and FT4 were measured in two groups. Results The level of serum hs-CRP in the experimental group was higher than that in the control group, while the levels of FT3 and FT4 in serum were significantly lower than those in the control group (P <0.05). There was a negative correlation between hs-CRP level and FT3 level (r = -0.643, P <0.05), hs-CRP level and FT4 level (r = -0.812, Also showed a significant positive correlation (r = 0.811, P <0.05). Conclusion Serum hs-CRP is negatively correlated with FT3 and FT4 levels, but FT3 and FT4 levels are positively correlated. It can be combined with the three in the clinical diagnosis of ischemic stroke, which can be used as a routine laboratory test.