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目的 探讨肾上腺皮质、髓质增生症的病理学特点及其鉴别诊断。方法 收集 4例肾上腺皮质、髓质增生症病例 ,观察其临床病理特点并进行免疫组化分析。结果 4例肾上腺见结节状增生的皮质细胞和弥漫增生的髓质细胞 ,其中髓质细胞免疫组化嗜铬素A、S 10 0、NSE呈阳性表达。结论 肾上腺皮质、髓质增生症有独特的病理学特点 ,根据其组织学改变和免疫组化染色结果 ,可与其它肾上腺疾病鉴别
Objective To investigate the pathological features and differential diagnosis of adrenal cortex and medullary hyperplasia. Methods Four cases of adrenal cortex and medullary hyperplasia were collected, and their clinical and pathological features were observed and analyzed by immunohistochemistry. Results Four cases of adrenal glandular nodular hyperplasia and proliferative myeloid cells were found. Immunofluorescence showed that the expression of chromogranin A, S 10 0 and NSE were positive in medullary cells. Conclusion Adrenal cortex, medullary hyperplasia has a unique pathological features, according to their histological changes and immunohistochemical staining, with other adrenal diseases can be identified