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【《医学世界报导》1991年8月】在华盛顿举行的内分泌学会会议上,有两个研究组报告应用胰岛素样生长因子1(IGF-1)治疗19例Ⅱ型糖尿病病人,能使血糖和胰岛素水平恢复正常。如果这两项初步研究结果得到证实,则 IGF 对膳食、运动或口服降血糖药所不能控制的Ⅱ型糖尿病可能是另一种值得吸引人的疗法。美国威斯康星州立大学的内科教授 Schalch 报告了他们对12例Ⅱ型糖尿病病人,皮下注射 IGF-1,剂量为90~160μg/kg,每日2次,连用5日。在治疗期间,空腹和餐后的血糖、胰岛素和 C 肽水平均明显降低,空腹血
Medical World Report, August 1991 At the Endocrine Society meeting in Washington, two study groups reported that 19 patients with type 2 diabetes treated with insulin-like growth factor 1 (IGF-1) The level returned to normal. If the results of these two preliminary studies are confirmed, IGF may be another attractive treatment for type 2 diabetes that can not be controlled by diet, exercise or oral hypoglycemic agents. Schalch, a professor of internal medicine at the University of Wisconsin, reported that in 12 patients with type 2 diabetes, IGF-1 was administered subcutaneously at a dose of 90-160 μg / kg twice daily for 5 days. During treatment, fasting and postprandial blood glucose, insulin and C-peptide levels were significantly lower, fasting blood