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本文利用 SRCA 方法检测了61例膀胱移行上皮癌,20例肾盂移行上皮癌,6例输尿管移行上皮癌细胞表面的 ABH 血型物质。ABH 血型物质的减少或缺失和膀胱移行上皮癌的分化,浸润程度有明显关系。22例距离癌基底部3cm 处的膀胱粘膜和同一个体肿瘤标本的 SRCA 试验结果符合率为77%,这些癌旁粘膜除3例为原位癌外,余均为不典型增生,这证明,膀胱移行上皮癌细胞表面 ABH 血型物质的减少或缺失,可以出现在组织学形态改变之前。不同分化程度的肾盂及输尿管移行上皮癌 SRCA 试验结果明显不同,但和肿瘤的浸润和转移未见明显关系。
In this paper, 61 cases of bladder transitional cell carcinoma, 20 cases of renal pelvis transitional cell carcinoma and 6 cases of ureteral transitional cell carcinoma ABH blood group substances were detected by SRCA method. ABH blood group reduction or loss of material and bladder transitional epithelial cancer differentiation, infiltration of a clear relationship. The coincidence rate of SRCA in 22 cases of bladder mucosa and tumor of the same individual at 3cm from the basal part of the tumor was 77%. The adjacent mucosa except the 3 cases were in atypical hyperplasia, which proved that the bladder Loss or deletion of ABH blood group substances on the surface of transitional epithelial cancer cells can occur before histological changes. Different degrees of differentiation of renal pelvis and ureter transitional cell carcinoma SRCA test results were significantly different, but with the invasion and metastasis of tumor no significant relationship.