1,3-二氧环辛烷-2-羧酸类三环化合物的合成及其除草活性

• 作 者: 李斌 满瀛 张宗俭 Colin M Tice Lori A.Spangler James Gallagher Lois M. Bryman Howard C. Smith Manuel V. Nunez
• 机 构: 沈阳化工研究院!沈阳110021,沈阳化工研究院!沈阳110021,沈阳化工研究院!沈阳110021,Rohm and Haas Company Spring House! PA 19477-090
• 出 处: 浙江化工
• 发表日期: 2000年S1期
• 关键词: 三环化合物 羧酸类 除草活性 环辛烷 杀草谱 合成 罗门哈斯 二苯并 除草剂 优化工作

12H－Dibenzo d,g 1,3 dioxocin－6－carboxylic acid is a patented herbicide (US4976770)With good pre－and post－emergence activity on dicot weeds and sedges． Structure activity studies were initiated with the goal of discovering more synthetically accessible analogs with improved unit activity and crop－weed selectivity．An improved procedure to prepare the lead compound was developed．Analogs were prepared in which both the tricyclic core and the carboxylic acid function were varied．The synthesis and screening results of these analogs will be presented．

12H-Dibenzo d, g 1,3 dioxocin-6-carboxylic acid is a patented herbicide (US4976770) With good pre-and post-emergence activity on dicot weeds and sedges. Structure activity studies were initiated with the goal of discovering more synthetically accessible analogs with improved unit activity and crop-weed selectivity. An improved procedure to prepare the lead compound was developed. Analogs were prepared in which both the tricyclic core and the carboxylic acid function were varied. The synthesis and screening results of these analogs will be presented.