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目的:探讨控释前列腺素E2栓剂普贝生用于足月妊娠引产的有效性及安全可行性。方法:将本院2008年12月2009年4月有引产指征的足月妊娠孕妇140例随机分成两组,研究组以普贝生用药,对照组行催产素静滴引产,比较两组产妇Bishop评分、引产费用、临产时间、破膜时间、分娩时间、总产程时间、分娩情况和结局以及新生儿体重及评分。结果:普贝生组用于足月妊娠引产效果明显优于对照组(P<0.01),研究组用药至临产时间显著短于对照组(P<0.01),引产成功率高于对照组,对母婴影响无显著差别。结论:普贝生是一种安全有效方便实惠的新型引产药物,对母婴没有明显不良影响,可在临床上应用。
Objective: To investigate the effectiveness and safety of controlled release prostaglandin E2 suppository in treating pregnancy induced abortion. Methods: A total of 140 full-term pregnant women with induction of labor induction in our hospital from December 2008 to April 2009 were randomly divided into two groups. The study group was treated with puberty and the control group received oxytocin intravenously. The two groups of maternal Bishop score, induction of labor costs, duration of labor, time to rupture of membranes, time of labor, duration of labor, delivery and outcome, birth weight and score. Results: The effects of induction of labor in full-term pregnancy in the Pubei group were significantly better than those in the control group (P <0.01). The study group was significantly shorter than the control group (P <0.01), and the successful rate of induction of labor was higher than that of the control group No significant difference between maternal and infant effects. Conclusion: Pu Bei Sheng is a safe, effective and convenient new induction drug for abortion. It has no obvious adverse effect on maternal and infant and can be applied clinically.