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早在1956年,已知肼苯达嗪可以改善心力衰竭患者的心、肾功能,但至今方被重视。本文目的为对比长期口服与静脉注射肼苯达嗪的疗效,以及停止口服后的结果。方法:(1)对象:16例,除2例为高血压性心脏病外,均为充血性心肌病。患者均经造影证实在室收缩功能严重减退,喷血分数<35%,10例的功能为Ⅲ-Ⅳ级,6例为Ⅱ级。测验期间不更动患者平素用药。包括强心、利尿、降压药。(2)给药方法:静脉注射16例。10毫克肼苯达嗪在10分钟内静脉注毕,注前及注毕后10、15、20分钟分别测定心率、
As early as 1956, hydralazine is known to improve heart and kidney function in patients with heart failure, but so far it has been taken seriously. This article aims to compare the long-term oral and intravenous hydralazine efficacy, and to stop the results after oral administration. Methods: (1) Subjects: 16 cases, except for 2 cases of hypertensive heart disease, were congestive cardiomyopathy. All patients underwent contrast-enhanced severe systolic dysfunction with a spurting score of <35%. The function of 10 cases was grade III-IV and six cases were grade II. During the test does not change patients usually medication. Including cardiac, diuretic, antihypertensive drugs. (2) administration method: intravenous injection in 16 cases. 10 mg hydralazine within 10 minutes intravenously completed before and after injection Note 10,15,20 minutes were measured heart rate,