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采用CGMS对142例T2DM患者进行连续3日的血糖监测。结果日内血糖高峰时间段为6.30～10.30(66.9%),早餐后1～2小时,晚餐后2小时;低谷值时间段为0.30～5.00(57.6%)。HbA1C与血糖总体平均值成正相关(r=0.81和0.84,P均<0.01),和TPG平均值成正相关(r=0.76,P<0.05)。胰岛素组低血糖发生率高于口服药组(X2分别为8.32和6.68,P均<0.01)。低血糖61例(43.0%)中36例(59.1%)为无症状性低血糖,使用CSII无警觉性低血糖发生率较高(54.6%)。结论应用CGMS能较好地评估血糖变化,有助于指导临床医师调控糖代谢紊乱。
142 patients with T2DM were monitored by CGMS for 3 consecutive days. Results The intraday peak blood glucose was 6.30-10.30 (66.9%), 1 to 2 hours after breakfast and 2 hours after dinner, while the low period was 0.30 to 5.00 (57.6%). HbA1C was positively correlated with the overall mean blood glucose (r = 0.81 and 0.84, P <0.01), and positively correlated with the mean TPG (r = 0.76, P <0.05). The incidence of hypoglycemia in insulin group was higher than that in oral medication group (X2 = 8.32 and 6.68, respectively, P <0.01). Hypoglycemia in 61 cases (43.0%), 36 cases (59.1%) asymptomatic hypoglycemia, CSII unobserved hypoglycemia was higher (54.6%). Conclusion The application of CGMS can better assess the changes of blood glucose, which can help clinicians to regulate the disorder of glucose metabolism.