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乙型肝炎免疫球蛋白M核心抗体(IgM抗-HBc)于乙型肝炎病毒(HBV)急性感染早期出现,滴度高,恢复期后逐渐下降,被IgG核心抗体(IgG抗-HBc)取代。高滴度IgM抗-HBc对确定HBV的急性(或近期)感染,以及对鉴别乙型肝炎表面抗原(HBsAg)携带者的急性非乙型肝炎,有十分重要价值。本文介绍我们应用酶联免疫吸附测定(ELISA)方法在正常人及各类
Hepatitis B immunoglobulin M core antibody (IgM anti-HBc) is present early in the acute phase of hepatitis B virus infection and has a high titer and gradually decreases after recovery and is replaced by IgG core antibody (IgG anti-HBc). High-titer IgM anti-HBc is of great value in determining acute (or near-term) HBV infection and in identifying acute non-Hepatitis B carriers of hepatitis B surface antigen (HBsAg) carriers. This article describes our application of enzyme-linked immunosorbent assay (ELISA) in normal humans and various types