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目的对大承气汤包装袋进行安全性研究。方法从煎液本身性质,如煎液的稳定性、pH值、灰分、重金属、有效成分等方面,对煎液予以考察,并且对包装袋吸附煎液有效成分、吸附量及包装袋残留物予以检测,采用高效液相色谱法、气相色谱法对中药汤剂包装袋予以分析。结果大承气汤经过10d低温及常温存放,汤剂性质稳定,产生沉淀较少,且pH值、灰分、重金属、有效成分均没有很大的变化,包装袋对煎液吸附量较少,对煎液有效成分不会产生很大影响,包装袋经过高温之后不会产生有害成分,且本身性质稳定,从不同角度予以分析,可以用于大承气汤包装。结论通过对大承气汤包装袋予以分析,为中药煎液包装袋安全性研究提供依据。
Objective To study the safety of Dachengqi Decoction bag. Methods The decoction was investigated from the properties of decoction itself, such as decoction stability, pH value, ash content, heavy metals, active ingredients and so on, and the effective components, Testing, using high performance liquid chromatography, gas chromatography decoction package to be analyzed. Results Dachengqi Decoction stored at low temperature and normal temperature for 10 days, the properties of the decoction were stable, less precipitation occurred, and there was not much change in pH, ash, heavy metals and active ingredients. Decoction of the active ingredient does not have a significant impact, after the bag does not produce harmful ingredients after high temperature, and its stable nature, from different angles to be analyzed, can be used for Da Cheng Tang packaging. Conclusion Through the analysis of Dachengqi Decoction bag, provide the basis for the safety study of Decoction package.