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左心室功能衰退是冠状动脉疾病死亡率最重要的预测指标之一,冠状动脉旁路移植术的目的之一是保持左室的正常功能和改善异常功能。本文比较稳定型心绞痛患者经内科和外科治疗后5年的静息时左室功能改变,并评价围术期和手术后晚期心肌梗塞以及移植血管通畅率对左室功能的影响。方法:686例症状持续6个月以上、经内科治疗3个月、以及静息和运动心电图呈缺血改变的稳定型心绞痛患者,随机分组进行内科和外科治疗。6个月内发生过心肌梗塞,动脉舒张压100毫米汞柱以上,左室室壁瘤或妨碍手术进行的其它明显器质性心脏病,或患有其它不能生存5年以上的疾病者,以及不稳定型心绞痛或充血性心力衰竭患者均予剔除。治疗约5年(平均5.2±0.6年)后,所有存活的
Left ventricular dysfunction is one of the most important predictor of coronary artery disease mortality, one of the purposes of coronary artery bypass grafting is to maintain the normal function of the left ventricle and improve abnormal function. This study compared left ventricular function at rest at 5 years after medical and surgical treatment in patients with stable angina and assessed the effects of perioperative and postoperative late myocardial infarction and graft patency on left ventricular function. Methods: Sixty-six patients with stable symptoms of angina pectoris who had been treated for more than 6 months with medical treatment for 3 months and resting and exercise ECG were randomly divided into two groups: medical and surgical treatment. Myocardial infarction within 6 months, arterial diastolic blood pressure above 100 mmHg, left ventricular aneurysm or other apparent organic heart disease preventing surgery, or other diseases that can not survive for more than 5 years, and Patients with unstable angina or congestive heart failure were excluded. After treatment for about 5 years (mean 5.2 ± 0.6 years), all survived