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目的探讨高频超声对动脉粥样硬化性脑梗死(ATCI)患者动脉斑块的评价作用。方法68例ATCI患者随机分为常规治疗(A)组和氟伐他汀治疗(B)组(常规治疗基础上,每晚口服氟伐他汀40mg);于治疗前及治疗后3个月用高频超声检测患者颈动脉斑块指数、内膜中层厚度(IMT)及收缩峰期血流速度(PSV)、舒张末期血流速度(EDV)、阻力指数(RI)、搏动指数(PI)等指标,并监测血脂变化。结果与A组相比,B组颈动脉稳定斑块数量增多,斑块指数、IMT下降,PSV、EDV增快,RI、PI下降(P<0.05或P<0.01);B组患者低密度脂蛋白(LDL-C)浓度较治疗前有明显降低(P<0.01)。结论颈动脉超声检测可用于评估药物对ATCI患者的治疗作用。
Objective To investigate the evaluation of arterial plaque in patients with atherosclerotic cerebral infarction (ATCI) by high frequency ultrasound. Methods Sixty-eight patients with ATCI were randomly divided into two groups: conventional treatment (A) and fluvastatin treatment (B) (on the basis of routine treatment, 40 mg of oral fluvastatin per night). Before and 3 months after treatment, The carotid plaque index, IMT, PSV, EDV, RI and PI of the patients underwent ultrasound examination. And monitor blood lipid changes. Results Compared with group A, the number of carotid artery plaque in group B was increased, plaque index, IMT decreased, PSV and EDV increased, RI and PI decreased (P <0.05 or P <0.01) Protein (LDL-C) concentration was significantly lower than before treatment (P <0.01). Conclusion Carotid ultrasonography can be used to evaluate the therapeutic effect of drugs on patients with ATCI.