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该气雾剂是混悬型三相气雾剂,是祖国传统中成药精品“六神丸”的现代新剂型.该成果将处方中所含不溶于抛射剂和潜溶剂中的药物制备成均匀分散的混悬型分散体系,采用先进的气流粉碎技术,使微粉粒度均小于10μm,不仅增强分散体系的稳定性,也大大增强了微粉药物在病灶部位的吸收度,并选用有利于药物稳定的表面活性剂和潜溶剂.经药理学试验证明,该气雾剂可明显抑制小鼠二甲苯引
The aerosol is a suspension type three-phase aerosol and is a modern new formulation of the traditional Chinese medicine “Lishin Pill” which is a traditional Chinese medicine product. This result will prepare a uniform dispersion of the drugs that are insoluble in the propellant and the latent solvent contained in the prescription. Suspension-type dispersion system adopts advanced jet crushing technology, so that the particle size of the powder is less than 10μm, which not only enhances the stability of the dispersion system, but also greatly enhances the absorption of the micropowder drug at the lesion site, and selects the surface activity that is favorable for drug stability. Agents and latent solvents. Pharmacological tests have shown that the aerosol can significantly inhibit mice xylene cited