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采用ＣｏｍｍｕｎｉｃａｔｉｏｎＢｏｘ大鼠模型研究了反复心理应激对大鼠儿茶酚胺（ＣＡ）和酪氨酸（Ｔｙｒ）代谢的影响，及补充Ｔｙｒ的作用。实验发现：反复心理应激使心理应激组（Ｓ组）和心理应激补充Ｔｙｒ组（ＳＴ组）第１、３、７ｄ２４ｈ尿ＣＡ排出量高于对照组（Ｃ组）（Ｐ＜００５）；而第１４ｄＳＴ组血浆和脑匀浆Ｔｙｒ含量分别高于Ｓ组和Ｃ组（Ｐ＜００１）。反复心理应激７ｄ时，Ｓ组大鼠旷场试验得分低于Ｃ组（Ｐ＜００５），产生行为缺陷，而补充Ｔｙｒ使ＳＴ组大鼠旷场试验得分降低有所减轻。
The effects of repeated psychological stress on the metabolism of catecholamine (CA) and tyrosine (Tyr) and the effect of Tyr supplementation in rats were studied by using the CommunicationBox rat model. The experimental results showed that repeated psychological stress increased urinary CA excretion of rats in psychological stress group (S group) and psychological stress-supplemented Tyr group (ST group) on the 1st, the 13th and the 24th day (P <0 05). The Tyr contents of plasma and brain homogenates in the 14th dST group were higher than those in the S and C groups (P <001), respectively. After repeated psychological stress for 7 days, the scores of open-field test in group S were lower than those in group C (P <005), resulting in behavioral deficits. However, supplementation of Tyr reduced the scores of open-field test in ST group.