甲状腺激素变化对急性创伤严重程度和预后的估价

• 作 者: 李景煜 林占堂 胡南方
• 机 构: 同济医科大学附属同济医院急诊外科,同济医科大学附属同济医院急诊外科,同济医科大学附属同济医院急诊外科
• 出 处: 同济医科大学学报
• 发表日期: 1989年S2期
• 关键词: 创伤严重程度 创伤 病人血清 四碘甲腺原氨酸 甲状腺激素 急性创伤 多发伤 三碘甲腺原氨酸 摄取比 变化水平

作者用放免方法测定了52例急性创伤病人血清中四碘甲腺原氨酸(T_4),三碘甲腺原氨酸(T_3),游离T_4指数(FT_4I),反T_3(rT_3),T_3摄取比率(T_3RUR)的水平,并测定35例正常人作对照。结果表明:创伤病人血清中T_4,FT_4I,T_3水平明显降低;rT_3,T_3RUR显著升高,同正常人比较,有极显著意义(P<0.001)。随创伤严重程度不同,血清中T_4,FT_4I,T_3RUR水平也随之变化。当rT_3值升高到一定程度(0.69nmol/L)时,死亡率极高。

The authors measured the levels of T_4, T_3, FT_4I, T_3 and T_3 in serum of 52 acute traumatic patients by radioimmunoassay (T_3RUR) levels, and measured 35 normal controls. The results showed that the levels of T_4, FT_4I and T_3 in the traumatic patients were significantly decreased; the levels of rT_3 and T_3RUR were significantly increased, which were significantly higher than those in normal controls (P <0.001). With the severity of trauma, the levels of T_4, FT_4I and T_3RUR in serum also changed. When the rT_3 value increased to a certain extent (0.69nmol / L), the mortality rate was extremely high.