论文部分内容阅读
目的探讨乳腺导管内乳头状肿瘤术中快速冰冻切片的形态学特征。方法手术治疗64例乳腺导管内乳头状肿瘤患者,均行术中快速冰冻切片、术后常规石蜡切片检查,将2种检查结果进行对比。结果术后组织病理诊断乳腺导管内乳头状瘤59例,非典型性乳头状瘤4例,导管内乳头状癌1例;术中快速冰冻切片确诊51例,延迟诊断12例均为上皮重度增生及非典型增生的病例,1例导管内乳头状癌误诊为导管内乳头状瘤;乳腺导管内乳头状肿瘤形态学特征表现为导管生长模式64例,乳头状结构47例,假浸润性结构12例,上皮增生及大汗腺化生18例。结论依据术中快速冰冻切片乳腺导管内乳头状肿瘤形态学特征表现有助于其诊断与鉴别诊断。
Objective To investigate the morphological features of intra-operative rapid frozen sections of intraductal papillary tumors. Methods Sixty-four patients with intraductal papillary tumors of the breast were surgically treated. All the patients underwent rapid frozen section during operation. Paraffin sections were performed routinely and the results of two tests were compared. Results Postoperative histopathological diagnosis of intraductal papilloma in 59 cases, atypical papilloma in 4 cases, intraductal papillary carcinoma in 1 case; rapid frozen section diagnosis of 51 cases, delayed diagnosis of 12 cases were epithelial hyperplasia And atypical hyperplasia, one case of intraductal papillary carcinoma was misdiagnosed as intraductal papilloma. The morphological features of intraductal papillary carcinoma were 64 cases of ductal growth, 47 cases of papillary and 12 infiltrative structures Cases, epithelial hyperplasia and apocrine metaplasia in 18 cases. Conclusion According to the intraoperative rapid frozen section intraductal papillary tumor morphological features contribute to its diagnosis and differential diagnosis.