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细菌性脑膜炎的全球负担主要是由于奈瑟脑膜炎球菌和肺炎链球菌的侵袭性感染造成的。发达国家在1987年引入b型流感嗜血杆菌(Hib)结合疫苗前,Hib是许多细菌性脑膜炎的病因。Hib结合疫苗降低了Hib发病率达80%或更多,这依赖于疫苗的普及程度。单价脑膜炎球菌C群(Men C)疫苗于1999—2000年上市,在英国降低了由Men C引起的侵袭性脑膜炎球菌病90%以上。现在有3个上市
The global burden of bacterial meningitis is mainly due to invasive infections with Neisseria meningitides and Streptococcus pneumoniae. Hib is the etiology of many bacterial meningitis before the introduction of the Hib conjugate vaccine in developed countries in 1987. Hib conjugate vaccines reduce the incidence of Hib by up to 80% or more, depending on the popularity of the vaccine. The monovalent Men C vaccine, marketed in 1999-2000, reduced the incidence of Meningococcal Meningococcal disease in the United Kingdom by more than 90%. There are 3 listings now