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目的探讨妊娠期糖尿病孕妇孕期干预对妊娠结局的影响。方法对2011年1月-2014年5月收治的妊娠期糖尿病患者238例进行分析,其中经过妊娠期糖尿病孕期干预的118例为干预组,未经过干预的120例为对照组。比较两组病例妊娠并发症及新生儿出生结局。结果干预组的妊娠期高血压、胎膜早破、羊水过多、产道感染的发生率分别为5.08%、3.39%、4.24%、2.54%,明显低于对照组(14.17%、20.00%、65.00%、10.00%),两组比较差异有统计学意义(P<0.05);干预组巨大儿、胎儿宫内窘迫、新生儿低血糖和高胆红素血症的发生率分别为1.69%、2.54%、0.85%、5.08%,明显低于对照组(20.83%、21.67%、7.50%、15.00%),两组比较差异有统计学意义(P<0.05)。结论对妊娠期糖尿病孕妇孕期干预可以明显减少母婴并发症,改善母婴围产结局。
Objective To investigate the effect of gestational diabetes during pregnancy on pregnancy outcomes. Methods A total of 238 cases of gestational diabetes mellitus admitted from January 2011 to May 2014 were analyzed. Among them, 118 cases of gestational diabetes mellitus during pregnancy were intervention group, while 120 cases of non-intervention group were control group. Pregnancy complications and neonatal birth outcomes were compared between the two groups. Results The incidences of gestational hypertension, premature rupture of membranes, polyhydramnios and birth canal infections were 5.08%, 3.39%, 4.24% and 2.54% in the intervention group, which were significantly lower than those in the control group (14.17%, 20.00%, 65.00 %, 10.00% respectively). There was significant difference between the two groups (P <0.05). The incidence of macrosomia, fetal distress, neonatal hypoglycemia and hyperbilirubinemia were 1.69%, 2.54 %, 0.85%, 5.08%, respectively, which were significantly lower than those in the control group (20.83%, 21.67%, 7.50%, 15.00%). There was significant difference between the two groups (P <0.05). Conclusion Pregnancy in pregnant women with gestational diabetes mellitus can significantly reduce complications of maternal and infant and improve the outcome of perinatal delivery.