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目的 :观察不同剂量尿激酶在溶栓治疗中的作用。方法 :应用尿激酶 (U K) 15 0万 u组与 5 0万 u× 3天组静脉溶栓治疗发病 2 4小时内的急性脑梗塞各 15例。结果 :UK15 0万 u组总有效率 5 3.3% ,与对照组相比差别无显著性 ;U K5 0万 u× 3天组总有效率 80 % ,与对照组相比差别有显著性。并发脑出血发生率 U K15 0万 u组 13.3% ,UK5 0万 u× 3天组6 .7%。结论 :认为 UK5 0万 u× 3天组对于病程 2 4小时内的急性脑梗塞有较好疗效。
Objective: To observe the effect of different doses of urokinase in thrombolytic therapy. Methods Fifteen patients with acute cerebral infarction within 24 hours after onset of intravenous thrombolysis were treated with 150,000 uU of urokinase and 500,000 u × 3 days respectively. Results: The total effective rate of UK1500u was 53.3%, which was not significantly different from that of the control group. The total effective rate was 80% in the U5000u × 3days group, which was significantly different from the control group. The incidence of intracerebral hemorrhage was 13.3% in the U-K1500u group and 6.7% in the U50-u00w3 day group. Conclusion: It is considered that the UK 50 000 u × 3 days group has a good effect on acute cerebral infarction within 24 hours of course of disease.